abstract：:The micromeres, the first cells to be specified in sea urchin embryos, are generated by unequal cleavage at the fourth cell division. The micromeres differentiate autonomously to form spicules and dispatch signals to induce endomesoderm in the neighbouring macromeres cells in the embryo. Using a calcium indicator Fura...

journal_title：Biology of the cell

authors： Yazaki I,Abe M,Santella L,Koyama Y

更新日期：2004-03-01 00:00:00

abstract：:The communication of calcium signals between cells is known to be operative between neurons where these signals integrate intimately with electrical and chemical signal communication at synapses. Recently, it has become clear that glial cells also exchange calcium signals between each other in cultures and in brain sl...

journal_title：Biology of the cell

authors： Braet K,Cabooter L,Paemeleire K,Leybaert L

更新日期：2004-02-01 00:00:00

abstract：:The lateral line of the zebrafish has many of the advantages that made the sensory organs of Drosophila a very productive model system: 1) it comprises a set of discrete sense organs (neuromasts) arranged in a defined, species-specific pattern, such that each organ can be individually recognized; 2) the neuromasts are...

journal_title：Biology of the cell

authors： Dambly-Chaudière C,Sapède D,Soubiran F,Decorde K,Gompel N,Ghysen A

更新日期：2003-12-01 00:00:00

abstract：:Our knowledge of cell signalling pathways in the molluscan immune system and their response to immunological challenge is currently poor. The present study focused on the Protein Kinase C (PKC) pathway in the immune cells (haemocytes) of Lymnaea stagnalis and its response following exposure to bacterial lipopolysaccha...

journal_title：Biology of the cell

authors： Walker AJ,Plows LD

更新日期：2003-11-01 00:00:00

abstract：:Netrins are secreted proteins that play a crucial role in neuronal migration and in axon guidance during the development of the nervous system. Netrin-1 has been shown to interact with the transmembrane receptors DCC and UNC5H and these receptors appeared of key importance in mediating the chemotropic activity of netr...

journal_title：Biology of the cell

authors： Mehlen P,Mazelin L

更新日期：2003-10-01 00:00:00

abstract：:A history of the early development of the confocal laser scanning microscope in the MRC Laboratory of Molecular Biology in Cambridge is presented. The rapid uptake of this technology is explained by the wide use of fluorescence in the 80s. The key innovations were the scanning of the light beam over the specimen rathe...

journal_title：Biology of the cell

authors： Amos WB,White JG

更新日期：2003-09-01 00:00:00

abstract：:In eukaryotes transcription and translation takes place in two different compartments separated by the nuclear envelope. Nuclear translation has been reported in several publications, however, all these published results have been criticized, particularly with respect to cytoplasmic contamination of the nuclei. We hav...

journal_title：Biology of the cell

authors： Cosson B,Philippe M

更新日期：2003-07-01 00:00:00

abstract：:RNA helicases of the DEAD-box and related families have been found to be required for all processes involving RNA molecules. Biochemical and genetic analyses have shown that at least two RNA helicases are required for translation initiation in yeast. Although it is generally believed that these enzymes are necessary t...

journal_title：Biology of the cell

authors： Linder P

更新日期：2003-05-01 00:00:00

abstract：:We have recently shown that staurosporine (ST) can trigger apoptosis of CaSki and HeLa cervical tumor cells from G2/M checkpoint, though the mechanism remains elusive. In this study, we reported that ST induced the inhibition of E6 and E7 viral oncogene and MDM2 expression, while it led to increased levels of p53, whi...

journal_title：Biology of the cell

authors： Bernard B,Prétet JL,Charlot JF,Mougin C

更新日期：2003-01-01 00:00:00

abstract：:Gap junctions are widely expressed in the various cell types of the central nervous system. These specialized membrane intercellular junctions provide the morphological support for direct electrical and biochemical communication between adjacent cells. This intercellular coupling is controlled by neurotransmitters and...

journal_title：Biology of the cell

authors： Rouach N,Avignone E,Même W,Koulakoff A,Venance L,Blomstrand F,Giaume C

更新日期：2002-11-01 00:00:00

abstract：:A general feature of the cell adhesion molecules belonging to the immunoglobulin family (Ig-CAMs) is to display a modular structure that provides a framework for multiple binding sites for other recognition molecules. Among this family, F3/contactin is a glycan phosphatidyl-inositol (GPI)-anchored molecule expressed b...

journal_title：Biology of the cell

authors： Falk J,Bonnon C,Girault JA,Faivre-Sarrailh C

更新日期：2002-10-01 00:00:00

abstract：:An interaction between human poly(A)-binding protein (PABP) et human eRF3 has been demonstrated using a double-hybrid approach and in vitro assays. Here, we show that the binding of both proteins is conserved through evolution. We also demonstrate that the last 39 C-terminal amino acids of PABP contain the interface t...

journal_title：Biology of the cell

authors： Cosson B,Berkova N,Couturier A,Chabelskaya S,Philippe M,Zhouravleva G

更新日期：2002-09-01 00:00:00

abstract：:The oligochaete annelids, belonging to the subfamily Tubificinae, produce two types of spermatozoa: eusperm (the fertilising ones) and parasperm, protecting and carrying the eusperm. The pathway for the production of the two types is common until the onset of meiosis, but then a regular meiosis produces eusperm, where...

journal_title：Biology of the cell

authors： Ferraguti M,Fascio U,Boi S

更新日期：2002-05-01 00:00:00

abstract：:Image cytometry was applied to study the intracellular localization of autofluorescence and the influence of an oxidative stress on this emission. K562 erythroleukemia cancer cells were analyzed with a microspectrofluorometer, coupled with a Argon laser (Ar+) (363 nm). From each cell, 15 x 15 emission spectra were rec...

journal_title：Biology of the cell

authors： Bondza-Kibangou P,Millot C,Dufer J,Millot JM

更新日期：2001-11-01 00:00:00

abstract：:Since almost two decades, it is known that progesterone is responsible of the release of the prophase I arrest of amphibian oocytes and leads to the activation of the universal MPF, through a puzzling transduction pathway. It involves negative regulation of the cAMP-dependent protein kinase (PKA) and synthesis of new ...

journal_title：Biology of the cell

authors： Karaiskou A,Dupré A,Haccard O,Jessus C

更新日期：2001-09-01 00:00:00

abstract：:The occurrence of the tubulin post-translational modification, polyglycylation, in stable microtubular structures was investigated during morphogenesis in two ciliates, Paramecium and Frontonia atra, belonging to the Epiplasmata group. This analysis was carried out by means of immunofluorescence and post-embedding imm...

journal_title：Biology of the cell

authors： Iftode F,Clérot JC,Levilliers N,Bré MH

更新日期：2000-12-01 00:00:00

abstract：:Interactions of cells with the extracellular matrix are essential for the control of tissue remodelling, cell migration, and embryogenesis. At the cell-extracellular matrix contact points, specialized structures are formed and termed focal adhesions, where transmembrane adhesion receptors provide a structural link bet...

journal_title：Biology of the cell

authors： Petit V,Thiery JP

更新日期：2000-10-01 00:00:00

abstract：:Peroxisomes are present in most eukaryotic cell types, and have different enzymatic content and metabolic functions throughout the life scale. The endosymbiotic origin of these DNA-devoid organelles is supported by evolutionary data concerning genes encoding not only most peroxisomal proteins, but also several transcr...

journal_title：Biology of the cell

authors： Latruffe N,Vamecq J

更新日期：2000-09-01 00:00:00

abstract：:ERM (ezrin/radixin/moesin) proteins, concentrated in actin rich cell-surface structures, cross-link actin filaments with the plasma membrane. They are involved in the formation of microvilli, cell-cell adhesion, maintenance of cell shape, cell motility and membrane trafficking. Recent analyses reveal that they are not...

journal_title：Biology of the cell

authors： Louvet-Vallée S

更新日期：2000-08-01 00:00:00

abstract：:Interaction of sperm and egg at fertilization induces well-coordinated molecular events including specific recognition between species, adhesion and fusion, that lead to the formation of a zygote, a totipotent cell that develops into a new individual. A calcium signal, common to a great number of species, from marine ...

journal_title：Biology of the cell

authors： Ciapa B,Chiri S

更新日期：2000-07-01 00:00:00

abstract：:Our recent data suggest that during auto- and allograft recognition in sponges (Porifera), cytokines are differentially expressed. Since the mitogen-activated protein kinase (MAPK) signal transduction modulates the synthesis and release of cytokines, we intended to identify one key molecule of this pathway. Therefore,...

journal_title：Biology of the cell

authors： Böhm M,Schröder HC,Müller IM,Müller WE,Gamulin V

更新日期：2000-04-01 00:00:00

abstract：:The daily rhythm in the activity of arylalkylamine N-acetyltransferase (AA-NAT) controls the rhythm in melatonin synthesis in the pineal gland. In the rat, transcriptional regulatory mechanisms play a major role in determining the observed pattern of AA-NAT gene expression. Remarkably, high levels of AA-NAT transcript...

journal_title：Biology of the cell

authors： Baler R,Covington S,Klein DC

更新日期：1999-12-01 00:00:00

abstract：:The activity and the tissue distribution of the oxygen radical producing enzyme xanthine oxidoreductase (XOR) were measured in the digestive gland of the common marine mussel Mytilus galloprovincialis Lmk along an annual cycle. No xanthine oxidase (XOX) activity could be measured, the enzyme only displaying xanthine d...

journal_title：Biology of the cell

authors： Cancio I,Cajaraville MP

更新日期：1999-11-01 00:00:00

abstract：:Genetic studies in the budding yeast have led to the molecular characterization of gamma-tubulin associated proteins and to the identification of orthologues in animal cells. While the gamma-tubulin complex is more complex in animal cells than in budding yeast, its function is probably maintained throughout evolution....

journal_title：Biology of the cell

authors： Tassin AM,Bornens M

更新日期：1999-05-01 00:00:00

abstract：:The centrosome of the slime mould Dictyostelium discoideum displays a morphology markedly different from centriolar centrosomes or yeast spindle pole bodies, while fulfilling the same conserved functions in the organization of the microtubule cytoskeleton. Recent advances suggest that the Dictyostelium centrosome may ...

journal_title：Biology of the cell

authors： Daunderer C,Schliwa M,Gräf R

更新日期：1999-05-01 00:00:00

abstract：:In the present study, we describe the structural and cytological changes observed in staggerer mutant olfactory bulbs, as compared to normal mice. On the basis of photonic and ultrastructural observations we tried to define the alterations induced by the mutation: i.e. a reduction of bulb size, a reduction in the volu...

journal_title：Biology of the cell

authors： Monnier Z,Bahjaoui-Bouhaddi M,Bride J,Bride M,Math F,Propper A

更新日期：1999-01-01 00:00:00

abstract：:The interaction of cells with extracellular matrix components contributes to their specific differentiation. We studied hepatic peroxisomes and their changing features during embryonic development, and we immunolocalized in the same tissue the extracellular matrix components laminin and collagen IV as well as the inte...

journal_title：Biology of the cell

authors： Depreter M,Nardacci R,Tytgat T,Espeel M,Stefanini S,Roels F

更新日期：1998-12-01 00:00:00

abstract：:The activation of M-phase promoting factor (MPF) in one-cell mouse embryo is independent from the nucleus. Other autonomous phenomena include the cortical activity observed at the end of the first cell cycle and the reorganization of the microtubule network. Here, we observed that the autonomous control of MPF activat...

journal_title：Biology of the cell

authors： Ciemerych MA,Tarkowski AK,Kubiak JZ

更新日期：1998-11-01 00:00:00

abstract：:I am pleased to contribute to this special issue of Biology of the Cell in honor of Yoshio Masui. Oocyte maturation remains a small enough and young enough field that the authors assembled for this issue can trace the entire development of the field over the last 30 years, beginning with the early demonstration by Mas...

journal_title：Biology of the cell

authors： Maller JL

更新日期：1998-10-01 00:00:00

abstract：:Detection of nucleic acid sequence at the ultrastructural level has allowed us to better understand the expression of genes in some fields of application in cell biology. In situ hybridization at the ultrastructural level can be carried out using three different methods: on vibratome sections before embedding in epoxy...

journal_title：Biology of the cell

authors： Le Guellec D

更新日期：1998-07-01 00:00:00

abstract：:Previous experiments have revealed a relatively weak electrostatic binding capacity of in vitro reconstituted intermediate filaments (IFs) as well as of natural IFs of whole cell mount preparations for purified ribosomal particles of mammalian origin. In order to demonstrate that such associations also occur in vivo, ...

journal_title：Biology of the cell

authors： Traub P,Bauer C,Hartig R,Grüb S,Stahl J

更新日期：1998-07-01 00:00:00

abstract：:A central issue in the understanding of Marfan syndrome deals with the functional architecture of fibrillin-containing microfibrils. Fibrillin-rich microfibrils are long extracellular matrix fibrillar components exhibiting a 50 nm periodic beaded-structure with a width of around 20-25 nm after rotary shadowing and a 1...

journal_title：Biology of the cell

authors： Hanssen E,Franc S,Garrone R

更新日期：1998-06-01 00:00:00

abstract：:Circulating glucocorticoid (GC) levels are thought to modulate the basal activity of pro-opiomelanocortin (POMC) neurons within the mediobasal hypothalamus (MBH) of the male rat. In a recent study we demonstrated that Fos-immunoreactivity (Fos-IR) was spontaneously induced throughout the dark phase of the light/dark c...

journal_title：Biology of the cell

authors： Jamali KA,Tramu G

更新日期：1997-12-01 00:00:00

abstract：:Phosphorylation of the transcription factor CREB appears as an important step in the signal transduction cascade that activates melatonin biosynthesis in the mammalian pineal organ. We have studied the mechanisms causing CREB phosphorylation by immunocytochemical and immunochemical demonstration of phosphorylated CREB...

journal_title：Biology of the cell

authors： Maronde E,Schomerus C,Stehle JH,Korf HW

更新日期：1997-11-01 00:00:00

abstract：:We have characterized the selectivity filter of the water channel aquaporin-1 (AQP1) of proximal straight tubules (PST), as an equivalent cylindrical structure with a diameter of approximately 4.5 A, where water molecules single file. We report here efforts to evaluate its length. PST were dissected from rabbit kidney...

journal_title：Biology of the cell

authors： Whittembury G,González E,Gutiérrez AM,Echevarría M,Hernández CS

更新日期：1997-08-01 00:00:00

abstract：:Previous studies suggest that oligodeoxynucleotide (ODN) cellular uptake is cell cycle-dependent which may have important implications in cancer cell targeting. To further our understanding of ODN transport and activity, this study examines the relationships between the cell cycle, ODN cellular uptake, intracellular t...

journal_title：Biology of the cell

authors： Wu-Pong S,Bard J,Huffman J,Jimerson J

更新日期：1997-07-01 00:00:00

abstract：:Apoptotic-like events could be rapidly induced by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) in cells of the mouse plasmacytoma cell line MPC-11 grown in serum-free medium. Indicators for apoptosis were morphological changes visualized by light and electron microscopy, such as chromatin condensation ...

journal_title：Biology of the cell

authors： Giese G,Schmidt J,Gilbert M,Albrecht R,Traub P

更新日期：1997-05-01 00:00:00

abstract：:The major finding of the present study is that the ultrastructural organization of the neuromuscular synapse can be modified by a small, 4-week-long, physiological increase in the locomotor activity of the extensor digitorum longus muscle of normal adult rats trained to walk. This study measures these plastic adaptati...

journal_title：Biology of the cell

authors： Tomas J,Santafé M,Lanuza MA,Fenoll-Brunet MR

更新日期：1997-03-01 00:00:00

abstract：:Arabinoxylans were localised by immunocytochemistry using polyclonal antibodies in the cell walls of the apical internode of maize after degradation in the rumen. In order to understand the significance of arabinoxylan in digestibility property, two lines of maize differing in digestibility were used. Wide variations ...

journal_title：Biology of the cell

authors： Migné C,Prensier G,Cornu A,Grenet E

更新日期：1996-01-01 00:00:00

abstract：:The quick-freeze, freeze-fracture, deep-etching and rotary replication techniques were used to analyze the structural organization of Giardia duodenalis. The surface of the flagella was rugous, in contrast to the cell body surface which was smooth. The ventral region was characterized in more detail, exposing the laye...

journal_title：Biology of the cell

authors： Kattenbach WM,Diniz Junior JA,Benchimol M,de Souza W

更新日期：1996-01-01 00:00:00